Oral Malignant Melanoma - A Case Report

Shwetha Vasanth Kumar, Niharika Swain


Oral malignant melanomas are quite rare. They are considered more aggressive than the cutaneous melanoma and have a poorer prognosis. Early diagnosis can be achieved by histological examination and immunohistochemical staining. It is most commonly reported in the older age group, has a slight male predilection and is commonly seen in the palate and gingiva with the maxillary arch being more commonly affected than the mandibular arch. The aim of this paper is to describe clinical and microscopic features of oral malignant melanoma and its further confirmation by immunohistochemical staining with vimentin, S-100 and HMB-45 in a seventeen year old adolescent female patient in the lower anterior region of the mandibular arch.


Malignant Melanoma; Neuroendocrine Tumors; Neuroectodermal Neoplasms; Melan-A; HMB45, S-100; Vimentin; Cytoskeletal Proteins.

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