An Atypical Myofibroblastic Tumor of the Nasal Cavity: A Case Report

Laurence Shapiro, Ines Velez, Michael Siegel


Myofibroblastic tumors are difficult lesions to diagnose and treat appropriately. The clinical, radiographic and histopathologic manifestations of the disease, usually suggest more aggressive entities. In numerous cases of myofibroblastic tumors, the microscopic interpretation is of a high grade malignant tumor while the clinical behavior may be that of a benign lesion. They may range from completely benign looking to atypical, pseudo-sarcoma or sarcomatous tumors. The malignant potential is also variable with benign, locally invasive and persistent recurrences. Rarely, metastases are encountered. The head and neck surgeon must be aware of the variable nature of these tumors. This diagnosis should be considered when inflammatory disease or other benign or malignant neoplasms are excluded. The purpose of this paper is to remind the health care professional that although these lesions may appear aggressive, in numerous cases the behavior is that of an indolent benign condition. It will prevent over-treatment resulting in unnecessarily radical and potentially mutilating surgery.Cases like this, while rarely reported, suggest that early intervention with myofibroblastic tumors and surgical excision with clear tumor margins is curative.


Myofibroblastic tumor, atypical tumor, nodular fasciitis

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