Palatal Perforation Resulted by Rhinocerebral Mucormycosis: A Case Report
Mucormycosis is a rare, opportunistic and potentially lethal fungal infection caused by saprobic organism of the class zygomycetes. Common predisposing factors for this disease include diabetes mellitus and immunosuppression. The most common reported form of the disease is rhinocerebral mucormycosis, which is characterized by progressive fungal invasion of the paranasal sinuses, hard palate, orbit, and brain. The fungi invade the wall of blood vessels, producing thrombosis and ischemia. Oral manifestations can be the early signs of rhinocerebral form. Early diagnosis and management is therefore paramount importance for the survival of the patients. Here we present a case report of 70 year old diabetic male patient who presented with a perforation in the palate, nasal discharge, periorbital cellulitis, and facial pain. Detailed clinical, radiographic, biochemical, histopathological examinations revealed a diagnosis of rhinocerebral mucormycosis.
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