Mucoepidermoid carcinoma:A clinicopathological review of 75 cases

Sana Mehmood Qureshi, Omer Sefvan Janjua, Sefvan Majed Janjua

Abstract


Purpose: To determine the frequency and clinico-pathological presentation of mucoepidermoid carcinoma (MEC).

Patients and Methods: The study included all the cases which presented to the department and were diagnosed as mucoepidermoid carcinomas in the last six years. Records of all the malignant tumors of salivary glands that presented during this period were analyzed and out of these the frequency of mucoepidermoid carcinoma was noted.  The data analysis included the age, gender, anatomical site of tumor and its histopathological grading. 

Results: A total of 151 malignant salivary gland tumors presented to our department in the last six years. Out of these, 75 were diagnosed as mucoepidermoid carcinomas. The frequency of 49.6% was noted. The age ranged from 06 to 67 years (mean 42.6+1.85years). 36 were males and 39 were females with a male to female ratio of 1:1.08. Regarding site of malignancy, it was observed that 56% of the tumors originated in Parotid gland. Minor salivary glands were the second most commonly involved site (34.7%). Out of these 75 cases, 38.7% were high grade, 13.3% intermediate grade and 48% were low grade malignancies.

Conclusion: Frequency of mucoepidermoid carcinoma was 49.6% among all the salivary gland malignancies with more than half of the tumors originating in parotid gland. Histopathologically, low grade type was the most common pattern observed (48%).


Keywords


Salivary Glands;Mucoepidermoid Carcinoma;Malignancy

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