A Case of Multiple Eosinophilic Granulomas of Jaws: A Diagnostic Challenge

Seema Sikka, Pranav Sikka, Devi Charan Shetty, Aadithya B Urs


Langerhans cell histiocytosis an infrequent disorder complex; includes Letterer-Siwe disease, Hand-Schuller-Christian disease and Eosinophilic granuloma. It has a relative incidence of approximately 2 - 5 cases per million inhabitants per year. Eosinophilic granuloma is the most benign and localized form, may be solitary or multiple, primarily involves the skull and the facial bones. Here, we are presenting a case of patient complaining of just mandibular pain and ulcerations in mouth, the principal differential diagnoses included advanced periodontal disease or a periapical abscess of dental or periodontal origin. But, it was finally diagnosed to be a case of eosinophilic granuloma on histopathology. This implies that a simple case resembling periodontitis can be a serious disease and can lead to grave consequences if not taken seriously.


Eosinophilic Granuloma;Bone Diseases;Langerhans-Cells;Histiocytosis;Hematologic Diseases;Leukocyte Disorders;Eosinophilia.

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