Parapharyngeal Space Schwannoma: Report of a Case with Brief Review

Meena Avinash Kulkarni, Yashwant Ingle, Varsha Sangle


Schwannomas are benign, encapsulated, slow-growing tumors originating from Schwann cells of the peripheral nerve sheath. Approximately 25-40% of cases occur in the head and neck region, of which one percent has been reported in the oral cavity. They are usually asymptomatic and malignant transformation is rare. Few cases of intraoral schwannoma occurring on the tongue, the floor of the mouth, palate, gingiva, vestibule, lips, salivary glands and the mental nerve region have been reported in the medical literature. This paper reports a rare presentation of an intraoral schwannoma located in the parapharyngeal space arising from the parotid gland in a 31- year-old female patient. 


Neurilemmoma; Oral; Pharyngeal; Peripheral Nerve Sheath Tumors; Schwann cells; Schwannoma.

Full Text:



Neville B, Damm DD, Allen CM, Bouquot J. Oral and Maxillofacial Pathology. 3rd ed. Philadelphia: Saunders; 2008. p. 526-7.

Pfeifle R, Baur DA, Paulino A, Helman J. Schwannoma of the tongue: report of two cases. J Oral Maxillofac Surg 2001;59:802-4.

Artzi Z, Taicher S, Nass D. Neurilemmoma of the mental nerve. J Oral Maxillofac Surg. 1991;49:196-200.

Chrysomali E, Papanicolaou SI, Dekker NP, Regezi JA. Benign Neural tumors of the oral cavity. Oral Surg Oral Med Oral Path Oral Radiol Endod 1997;84:381-390.

Avi Khafif, Yoram Segev, Daniel M. Kaplan, et al. Surgical management of parapharyngeal space tumors: A 10-year review. Otolaryngology - Head and Neck Surgery 2005;132:401-6.

Chang SC, Schi YM. Neurilemmoma of the vagus nerve: a case report and brief literature review. Laryngoscope. 1984;94(7):946-9.

Franz M. Enzinger, Sharon W. Weiss. Soft Tissue Tumours. 4th Ed. Mosby Elsevier; 2001, p 1146-1167.

Nakasato T, Katoh K, Ehara S, Tamakawa Y, Hoshino M, Izumizawa M, et al. Intraosseous neurilemmoma of the mandible. Am J Neuroradiol 2000;21(10):1945-7.

Subhashraj K, Balanand S, Pajaniammalle S. Ancient schwannoma arising from mental nerve. A case report and review. Med Oral Pathol Oral Cir Buccal 2009;14(1):E12-4.

Chrysomali E, Papanicolaou S, Dekker N, Regezi J. Benign neural tumors of the oral cavity: a comparative immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;84(4):381-90.


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Indexed In Ebscohost Index Copernicus UlrichsWebOpenJGateGoogle Scholar DOAJ Gale Cengage Learning Research Gate
System Developed By Stanford University Arizona State University Simon Fraser University Canadian Centre For Studies In Publishing University of British Columbia - Faculty of Education
W3C XHTML v1.0 Verified W3C verified Valid CSS v2.1 PHP5 Enabled Made On Mac Apache Enabled MySQL Powered
Published by Celesta Software Pvt Ltd