Central Odontogenic Fibroma: A Case Report and Review of Literature

Prafulla Tulshidas Gaikwad, Meena Milind Kulkarni, Harish Saluja, Aatul Nikam, Sushil Yemle, Saurabh L Sabnis


Central odontogenic fibroma is an extremely rare benign tumor, accounting for less than 0.1% of all odontogenic tumors.  Clinically, the lesion is slow growing and produces cortical expansion. Radiologically, the most common finding is multilocular radiolucency. Histologically, the lesion is characterized by mature collagen fibers and numerous fibroblasts. COF responds well to conservative surgical excision with no tendency for recurrence. Here, a case of central odontogenic fibroma of the maxilla in a 15-year-old boy is described. The lesion was an asymptomatic swelling with well-defined borders covered by normal mucosa. The lesion presented as a unilocular radiolucency with foci of radio opacity in relation to the root of the maxillary anterior teeth. The lesion was surgically removed and analyzed histopathologically. There were no postoperative complications.


Odontogenic Fibroma; Benign Neoplasm; Fibrous Tissue; Desmoplastic; Fibroblasts.

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