Correlation of Salivary Glucose Levels with Dental Caries: A Biochemical Study

Pavitra Ajit Vibhakar, Sangeeta R Patankar, Monica Yadav, Parag Vibhakar


Context: Oral fluids are often called the ‘mirror of the body’ or ‘window on health status’ and are the perfect medium to be explored for health and disease surveillance. Saliva is an organic fluid that is easy to collect by non-invasive methods and is not costly to preserve. Elevated levels of blood glucose may cause oral alterations such as: a higher incidence of cavities, periodontal diseaseand candidiasis. Aim: Evaluate the levels of salivary glucose and their effect on dental caries. Settings and Design: Thirty nine patients were randomly selected and saliva was collected by the spitting method with all the necessary precautions. The saliva was then centrifuged and dried. The salivary glucose levels were measured by using the ERBA® GOD-POD and readings were obtained from ERBA® CHEM 5 analyzer in mg/dl. The data thus obtained was statistically analyzed by Pearson’s Correlation Test. Results: A significant correlation was obtained between the salivary glucose levels and dental caries, salivary glucose and the age of the patients and the Decayed Missing Filled teeth Index (DMFT index) and Age of the patients. Conclusions: Salivary glucose levels increase with increasing DMFT index and play a significant role in high caries incidence. Modification of the already available glucose monitoring kits to suit saliva could provide a novel chair-side aid in patient education and dental caries prevention.



Saliva, Glucose Levels, Dental Caries, Salivary Glucose, GOD-POD technique, DMFT index

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