Myofibroma of Mandible: A Diagnostic Dilemma

Purwa Bhavana Patil, Bhavana Bharambe, Aditi Beke


Intraosseous myofibroma is a rare tumour characterised by localised or generalised proliferation of fibroblastic tissue. Bony lesions are common in mandible and maxilla. Histopathology revealed proliferation of streaming and whorled fascicles of spindle cells around slit-like vascular spaces in collagenous stroma. The spindle cells were immunopositivity for vimentin and smooth muscle actin, but were negative for desmin and S-100 protein. Myofibroma appears alarming clinically due to its fast growth which may mimic a malignancy. However, it is completely benign and is usually treated by complete surgical excision with excellent prognosis. This tumor was positive for vimentin and SMA. Our patient has shown no signs of recurrence during 2 years of follow-up.


Myofibroma; Mandible; Benign Tumor; Intraosseous; Biphasic Tumor; Myofibroblast

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