Glandular Odontogenic Cyst Presenting as an Aggressive Multifocal Lesion

Atulkumar Ashokrao Patil, Suresh Ramchandra Barpande, Jyoti Dilip Bhavthankar, Mandakini S. Mandale


Glandular odontogenic cyst is a rare developmental lesion considered as a distinct entity because of its uncommon histopathological characteristics. It was formerly denominated as “Sialo-odontogenic cyst” because of probable origin from the salivary gland tissues. But, World Health Organization includes glandular odontogenic cyst as a developmental odontogenic cyst to support an odontogenic origin. The low incidence of Glandular odontogenic cyst (0.2% of odontogenic cysts) is because of not only its rarity, but principally to the fact that its main characteristics are also found in other pathologic entities there by generating controversial diagnosis. Although it is relatively rare, correct diagnosis is of major clinical importance, since Glandular odontogenic cyst has an aggressive potential, a high incidence of cortical perforation and relatively high rate of recurrence. So, clear definition of histopathological criterion is necessary to make a final diagnosis of Glandular odontogenic cyst. Documentation of more and more cases will help in exploring the definite histopathologic criteria for this lesion. The present case report is a case of Glandular odontogenic cyst in a 51 year old male patient with multiple cystic lesions involving the entire left mandibular ramus area and also to highlight the clinical, radiological and histopathological findings of Glandular odontogenic cyst.


Glandular Odontogenic Cyst; Immunohistochemical Markers; Sialo-Odontogenic Cyst; Mucoepidermoid Carcinoma; Odontogenic; Cysts.

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