Mandibular Cholesterol Granuloma Mimicking a Dentigerous Cyst

Ana Carolina Mesquita Netto, João Artur Ricieri, Camila de Nazaré Alves de Oliveira, Ronaldo Raivil Arruda, Ricardo Santiago Gomez, Ricardo Alves Mesquita


Cholesterol granuloma is an inflammatory foreign body reaction to cholesterol crystals. In this case report, it was described a rare cholesterol granuloma associated with a crown of the impacted tooth, resembling an early dentigerous cyst. Histopathologically, a large collection of longitudinal clefts could be observed, which proved to be cholesterol crystals surrounded by foreign body giant cells and macrophages filled with hemosiderin. The lesion and the third molar were fully excised. The patient is currently under follow-up and is free of disease.


Cholesterol Granuloma; Cholesterol Crystals; Dentigerous Cyst; Foreign Body;

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Leon ME, Chavez C, Fyfe B, Nagorsky MJ, Garcia FU. Cholesterol granuloma of the maxillary sinus. Arch Pathol Lab Med. 2002;126: 217-9.

Chao TK. Cholesterol granuloma of the maxillary sinus. Eur Arch Otorhinolaryngol. 2006;263:592-7.

Kaffe I, Littner MM, Buchner A, Friedman M. Cholesterol granuloma embedded in an odontoma of the maxilla. J Oral Maxillofac Surg. 1984;42:319-22.

Lee JH, Alrashdan MS, Ahn KM, Kang MH, Hong SP, Kim SM. Cholesterol granuloma in the wall of a mandibular dentigerous cyst: a rare case report. J Clin Exp Dent. 2010;2:88-90.

Hirschberg A, Dayan D, Buchner A, Freedman A. Cholesterol granuloma of the jaws. Int J Oral Maxillofac Surg.1988;17:230-1

Jones AV, Craig GT, Franklin CD. Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period. J Oral Pathol Med. 2006;35:500-7.

Graham J, Michaels L. Cholesterol granuloma of the maxillary antrum. Clin Otolaryngol Allied Sci. 1978;3:155-60.

Gunes HA, Almac A, Canbay E. Cholesterol granuloma of the maxillary antrum. Laryngol Otol. 1988;102:630-2.

Main TS, Shimada T, Lim DJ. Experimental cholesterol granuloma. Arch Otolaryngol. 1970;91:356-9.

Ramesh G, Dave A, Singh KD, Nagarajappa R. Dentigerous cyst involving multiple teeth in non syndromic patients and cholesterol granuloma - A Review. Int J Oral & Maxillofac Pathol. 2010;1:13-6.

Kotrashetti VS, Kale AD, Bhalaerao SS, Hallikeremath SR. Histopathologic changes in soft tissue associated with radiographically normal impacted third molars. Indian J Dent Res 2010;21:385-90.

Stanley HR, Alattar M, Collett WK, Stringfellow HR Jr, Spiegel EH. Pathological squeal of "neglected" impacted third molars. J Oral Pathol. 1988;17:113-7.

Dachi SF, Howell FV. A survey of 3,874 routine full-month radiographs. II. A study of impacted teeth. Oral Surg Oral Med Oral Pathol. 1961;14:1165-9.

Kim J, Ellis GL. Dental follicular tissue: misinterpretation as odontogenic tumors. J Oral Maxillofac Surg. 1993;51:762-8.

Stephens RG, Kogon SL, Reid JA. The unerupted or impacted third molar-a critical appraisal of its pathologic potential. J Can Dent Assoc. 1989;55:201-7.

Eliasson S, Heimdahl A, Nordenram A. Pathological changes related to long-term impaction of third molars. A radiographic study. Int J Oral Maxillofac Surg. 1989;18:210-2.


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