Orthokeratinised Odontogenic Cyst Mimicking Mandibular Paradental Cyst: A Rare Case
The orthokeratinised odontogenic cyst is a rare epithelial developmental cyst of the jaws. This lesion resembles odontogenic keratocyst which is commonly found in the mandible, and can become quite large due to its rapid growth and its extension into the adjacent structures. Clinically the parakeratinising odontogenic keratocyst’s are characterized by aggressive growth and tendency to recur after surgical treatment in contrast to orthokeratinised odontogenic keratocyst. We report a rare case with no clinical signs and symptoms other than pain in relation to left posterior mandibular region. The intraoral soft tissues adjoining to third molar are absolutely normal, whereas radiographic appearance were suggestive of Paradental cyst and periodontal cyst. The excised tissue specimen diagnosed as orthokeratinised odontogenic cyst.
Philipsen HP. Keratocystic odontogenic tumor. In: Barnes L, Eveson JW, Reichart PA, Sidransky D, Eds. World Health Organization Classification of Tumours: Pathology and Genetics Head and Neck Tumours. Lyon, France: IARC Press; 2005:306-7.
Ackermann G, Cohen MA, Altini M. The paradental cyst: a clinicopathologic study of 50 cases. Oral Surg Oral Med Oral Pathol 1987;64:308–12.
Kramer IR, Pindborg JJ, Shear M. The WHO Histological Typing of Odontogenic Tumours. A commentary on the Second Edition. Cancer. 1992;70(12):2988-94.
Pindborg JJ, Hansen J. Studies on odontogenic cyst epithelium. 2. Clinical and roentgenologic aspects of odontogenic keratocyst. Acta Pathol Microbiol Scand. 1963;58:283-94.
Dong Q, Pan S, Sun LS, Li TJ. Orthokeratinized odontogenic cyst: A Clinicopathologic study of 61 cases. Arch Pathol Lab Med. 2010;134:271-5.
Chrcanovic B R, Reis B M, Freire-Maia B, Paradental (Mandibular Inﬂammatory Buccal) Cyst. Head and Neck Pathol 2011;5:159–64.
Philipsen HP, Reichart PA, Ogawa I, Suei Y, Takata T. The inflammatory paradental cyst: a critical review of 342 cases from literature survey, including 17 cases from the authors’ files. J Oral Pathol Med 2004;33:147–55.
Crowley TE, Kaugars GE, Gunsolley JC. Odontogenic keratocysts: a clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg. 1992;50(1):22-6.
Byatnal A, Natarajan J, Narayanaswamy V, Radhakrishnan R. Orthokeratinized odontogenic cyst critical appraisal of a distinct entity. Braz J Oral Sci 2013;12(1):71-5.
Ogden GR, Chisholm DM, Kiddie RA, Lane DP. p53 protein in odontogenic cysts: increased expression in some odontogenic keratocysts. J Clin Pathol 1992;45:1007-10.
Shear M and Speight M Paul. Cyst of the oral and maxillofacial regions; 4th edition Blackwell Munksguard 2007.
Baghaei F, M Eslami, D Sadri. Evaluation of Ki-67 Antigen and Protein P53 Expression in Orthokratinized and Parakratinized Odontogenic Keratocyst. Journal of Dentistry, Tehran University of Medical Sciences 2004;1:53-8.
Lo Muzio L, Santarelli A, Caltabiano R, Rubini C, Pieramici T, Fior A, et al. P63 expression in odontogenic cysts. Int J Oral Maxillofac Surg. 2005;34:668–73.
Ozveren A, Tuskan C, Yaltirik M, Atalay B, Erseven G. Expression of the Tumour Suppressor Gene p53 in Odontogenic Cysts. Turk J Med Sci 2003:33:243-7.
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 3.0 License.
|Published by Celesta Software Pvt Ltd|