Evaluation of Histopathological Subtypes of Ameloblastoma in a Tertiary Institution in Southern Part of Nigeria

Cornelius Azekanabo Iyogun, Gabriel Ukegheson, Olufemi Gbenga Omitola


Background: Ameloblastoma is the most frequent odontogenic tumour reported in Nigeria. It is a slow growing locally invasive tumor which though rarely undergoes metastasis, but is clinically persistent. Aim: The aim of this study was to evaluate the prevalence of the various histopathological subtypes of ameloblastoma seen at the Oral Pathology department of the University of Port Harcourt Teaching Hospital and compare it with other studies in Nigeria and elsewhere. Materials and Methods: This is a five year (2008-2013) retrospective study of all histopathologically diagnosed ameloblastoma at the Oral Pathology department of the University of Port Harcourt Teaching Hospital, Port Harcourt. Lesions were categorized using the 2005 World Health Organization classification of odontogenic tumours. Results: Within the study period, there were 52 cases of ameloblastoma out of a total of 63 odontogenic tumors seen. The patients’ age ranged from 7 – 65 years with a mean age of 28.5±14.6 years. There was equal sex predilection. Solid/multicystic ameloblastoma was the most prevalent 30(57.7%) and mandible was the predominant site with 43(82.7%) cases. Solid/multicystic ameloblastoma were more in females while unicystic ameloblastoma were more in males. Solid/multicystic and unicystic ameloblastoma were predominantly seen in the mandible. There was no case of malignant ameloblastoma or ameloblastic carcinoma. Conclusion: Solid/multicystic ameloblastoma was the most prevalent with higher incidence in females. The mandible was the commonest site of occurrence.


Ameloblastoma; Histological; Prevalence; Unicystic; Multicystic; Odontogenic.

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