Ameloblastoma with Multiple Histologic Variants: A Case Report with Review of Literature

Priya Sahni, Kruti C Patel, Ronak J Patel, Anil R Patel


Ameloblastoma is the second most common true neoplasm of odontogenic epithelial origin. Its incidence, approximately 1% of all oral tumours and 18% of all odontogenic tumours, combined with its clinical behavior, makes ameloblastoma the most significant odontogenic neoplasm. The ameloblastoma histopathologically presents with variable features. Hybrid lesion in ameloblastoma is comparatively a newer histopathologic variant and the occurrence of the lesion is not frequently seen. The present case is characterized by stromal desmoplasia and osteoplasia with classical follicular islands, granular and acanthomatous differentiation in the collision with luminal and intraluminal unicystic ameloblastoma with features of Calcifying Odontogenic Cyst ex ameloblastoma in a tumor arising in a 50-year-old male patient.


Acanthomatous; Ameloblastoma; Desmoplasia; Follicular; Hybrid; Odontogenic Tumor.

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