A silent killer in the laboratory – Formaldehyde: Review of effects and management.

Jayalakshmi Kumaraswamy, RaviKumar Hirusappa, Jaya Naidu, Raju Raghavendra

Abstract


Despite the known toxicity of formaldehyde and its potential health effects, laboratory workers and others have little enthusiasm for reducing or replacing the formaldehyde working solution. The responsibility of preventing health hazards is by both management and laboratory workers. It is the responsibility of the laboratory workers to understand and adopt good laboratory practices to achieve a healthy environment. It is important to have good toxicological and inflammability profiles that permit the safe use of formaldehyde. The aim of this review is to summarize the various applications, potential hazards and management of formaldehyde effects in the laboratories.


References


Shameena PM, Dhanalakshmi J, S Sudha. Safety and first aid in Laboratory – a brief outline. Available at www.ompj.org/619-pgO-jul-dec-2010 issue-html.

McCarthy K, Mclaughlin D, Montgomerg D, Munsell P, Schuster M, Wood M. “Keratin – Based” Hair Smoothing products and the presence of formaldehyde. Available at www.orosha.org/pdf/Final_Hair_Smoothing_Report.pdf.

Handling formaldehyde hazards. Shannon Decamp. Available at www.technetrain.net/Articles/part4.pdf

John D Bancroft, Marilyn Gamble. Theory and practice of Histological Techniques. 6th ed, 2008, Elsevier.

James H. Bedino. Formaldehyde exposure hazards ad health effects: A comprehensive review for embalmers. Expanding Encyclopedia of Mortuary practices. An official publication of the Research and Education Department, The champion company. Spring field OH 45501, 2004, 2633-49.

From: www.champion-newera.com/CHAMP.PDF/encylo650.pdf

Steven Bliss. Formaldehyde gas hazards indoors, Best practices guide to Residential construction. Available at www.inspectapedia.com/.../FormaldehydeGuide.htm

Cora Roelofs, Elizabeth Harriman, Michael Ellenbecker. Alternatives for significant uses of formaldehyde in Massachusetts. Available at http://www.eoearth.org/article/Alternatives_for_significant_uses_of_formaldehyde_in_Massachusetts.

Formaldehyde and Cancer risk – National Cancer Institute. Available at www.cancer.gov/Cancertopics/Factsheet/Risk/Formaldehyde

Mark S Dykewicz, Roy Patterson, David W Cugell, Kathleen E Harris and Anna Fang Wu. Serum IgE and IgG to formaldehyde-human serum albumin: Lack of relation to gaseous formaldehyde exposure and symptoms. J Aller clin Immuno 1991;89(1):48-57.

Mirabelli MC, Holt SM, Cope JM. Anatomy laboratory instruction and occupational exposure to formaldehyde. Occup Environ Med, 2010;68(5):375-8.

International Agency for Research on Cancer (June 2004). IARC Monographs on the evaluation of Carcinogenic Risks to Humans volume 88 (2006): Formaldehyde, 2-Butoxyethanol and 1-tert-Butoxypropan-2-01. Retrieved October 5, 2010 From: http://monographs.iarc.fr/ENG/Monographs/Vol88/index.php

Beane Freeman L, Blair A, Lubin JH, et al. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. The National Cancer Institute Cohort. J Natl Cancer Inst 2009;101(10):751-61.

Hauptmann M, Lubin JH, Stewart PA, Hayes RB, Blair A. Mortality from solid cancers among workers in formaldehyde industries. American Journal of Epidemiology 2004; 159(12):1117-30.

Hauptmann M, Lubin JH, Stewart PA, Hayes RB, Blair A. Mortality from lymphometapoietic malignancies and brain cancer among embalmers exposed to formaldehyde. J Natl Cancer Inst 2009;101(24):1696-1708.

Hauptmann M, Lubin JH, Stewart PA, Hayes RB, Blair A. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. J Natl Cancer Inst 2003;95(21):1615-23.

Pinkerton LE, Hein MJ, Stayner LT. Mortality among a cohort of garment workers exposed to formaldehyde: An update. Occup Environ Med 2004;61:193-200.

Coggon D, Harris EC, Poole J, Palmer KT. Extended follow-up of a cohort of British chemical workers exposed to

formaldehyde. Journal of the National Cancer Institute 2003; 95(21):1608-15.

Terry Martin. Formaldehyde in Cigarette Smoke. Updated August 14, 2010. Available at quitsmoking.about.com//chemicalsinsmoke/…/formal_dehyde/.htm

FP Edwards, AR Campbell. Removal of formaldehyde and xylene fumes from histopathology laboratories: a functional approach to the design of extraction systems. J Clin Pathol 1984; 37:401-8.

Heather Neuharth. Formaldehyde safety programs in Medical Schools. Updated: June/2010. Available at, http://www.ehow.com/list_6577419_formaldehyde_safety_programs_medical_schools html#ixzz1GNbt395K

Herb Rosenberg, Warren Fitch. How to reduce the level of formaldehyde in the Zoology lab. Page 357-360, in Tested

studies for laboratory teaching, volume 19 (S.J. Karcher, Editor). From: Association for Biology Laboratory Education (ABLE) http://www.200.utornto.ca/able.

Available at Equipment Bio-Decontamination service (EBDS)/29/03/2006-09:37:53 from www.pharmaceutical_int.com/.../equipment_bio_decontamination_service.


Full Text: PDF HTML XML

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Indexed In Ebscohost Index Copernicus UlrichsWebOpenJGateGoogle Scholar DOAJ Gale Cengage Learning Research Gate
line
System Developed By Stanford University Arizona State University Simon Fraser University Canadian Centre For Studies In Publishing University of British Columbia - Faculty of Education
W3C XHTML v1.0 Verified W3C verified Valid CSS v2.1 PHP5 Enabled Made On Mac Apache Enabled MySQL Powered
Published by Celesta Software Pvt Ltd