Cherubism: A Rare Case Report and Literature Review

Abstract

Cherubism is a rare developmental jaw condition that is generally inherited as an autosomal dominant trait with high penetrance but variable expressivity. It is a benign disease of bones affecting the jaws and giving a characteristic cherubic appearance to the patient. Recent genetic studies revealed that cherubism is a genetically mediated disorder first reported at 1933. It is a self limiting bony growth which usually begins to slow down when the patient reaches five years of age, and stops by the age of 12-15 years. At puberty the lesion begins to regress. The treatment of cherubism is still controversial and it is said that the disease will regress itself and after regressing if any asymmetry is there then the bony deformity can be corrected by decortications of bone and osseous shaving. This article presents a rare case report of 12 years old child who had started developing cherubism from the age of five years and till the age of twelve years showed no signs of regression. Also it involves review and recent development in the literature of cherubism.